Centella Asiatica – One of the Most Well-Researched Ingredients Supporting Skin Regeneration

Why Does Centella asiatica Play Such an Important Role in Modern Cosmetology?

Modern cosmetology increasingly uses active ingredients whose effectiveness has been confirmed by scientific research. One of the best-known is centella asiatica, a plant valued for many years for its regenerative, anti-inflammatory, and anti-aging properties.

Numerous studies indicate that Centella Asiatica (Centella asiatica) supports the skin’s natural repair processes, stimulates collagen synthesis, strengthens the protective barrier, and improves skin elasticity and firmness. As a result, it is widely used in professional cosmetology treatments.

What Is Centella Asiatica (Centella asiatica)?

Centella asiatica is a perennial herbaceous plant that occurs naturally in tropical and subtropical regions of Asia, Africa, and Australia.

In cosmetology, ingredients derived from this plant are used due to their richness in triterpene saponins, flavonoids, polysaccharides, amino acids, and minerals.

The highest biological value is exhibited by triterpenes, which are responsible for most of the documented regenerative and anti-aging properties.

Key Active Ingredients

The best-known biologically active substances include:

    • asiaticoside,
    • madecassoside,
    • asiatic acid,
    • madecassic acid.

Scientific studies indicate that these compounds:

    • support collagen synthesis, especially type I collagen,
    • stimulate the production of hyaluronic acid and extracellular matrix components,
    • increase hydroxyproline content, a marker of collagen synthesis,
    • support microcirculation,
    • reduce inflammatory processes,
    • strengthen blood vessel walls,
    • protect cells from oxidative stress.

Did You Know?

Centella asiatica is one of the most thoroughly researched active ingredients used in modern regenerative cosmetology. The results of numerous studies confirm its beneficial effects on wound healing processes, restoration of the skin barrier, and improvement of overall skin quality.

How Does Centella Asiatica Affect the Skin?

The most characteristic effect of centella asiatica is its support of the skin’s natural regenerative processes.

Its active ingredients stimulate fibroblast activity responsible for collagen and elastin production, support extracellular matrix reconstruction, and improve the organization of collagen fibers.

Regular use of products containing ingredients derived from centella asiatica may contribute to:

    • improved skin firmness,
    • increased elasticity,
    • reduced visibility of fine wrinkles,
    • improved hydration levels,
    • increased resistance of the skin to external factors,
    • support of regenerative processes.

Support for Sensitive and Problematic Skin

Thanks to its regenerative and anti-inflammatory properties, centella asiatica is used in the care of:

    • sensitive skin,
    • reactive skin,
    • acne-prone skin,
    • skin with an impaired hydrolipid barrier,
    • skin requiring regeneration after cosmetology procedures,
    • skin prone to atopic dermatitis.

It may also support the care of skin prone to psoriasis; however, it is not a treatment for this condition.

Anti-Aging Effects

One of the most well-documented effects of centella asiatica is its support of processes responsible for maintaining a youthful skin appearance.

Studies show that the active compounds of this plant:

    • stimulate fibroblast activity,
    • support collagen synthesis,
    • improve skin elasticity,
    • support extracellular matrix reconstruction,
    • reduce the effects of photoaging.

As a result, the skin gradually regains better tone, resilience, and a more even complexion.

Anti-Inflammatory Properties

Chronic low-grade inflammation (inflammaging) is currently recognized as one of the mechanisms responsible for accelerated skin aging.

Studies indicate that the active ingredients of centella asiatica may:

    • reduce redness,
    • alleviate irritation,
    • support the restoration of the hydrolipid barrier,
    • improve hydration levels,
    • support the skin’s natural defense mechanisms.

Did You Know?

An increasing number of studies indicate that reducing chronic skin inflammation may play a significant role in slowing down the aging process. Therefore, Centella asiatica is one of the most frequently used ingredients in modern regenerative therapies.

Effect on Microcirculation and Skin Remodeling

Research suggests that centella asiatica has a beneficial effect on microcirculation and connective tissue metabolism.

For this reason, it is also used in products supporting the care of:

    • scarred skin,
    • skin with stretch marks,
    • skin with post-inflammatory hyperpigmentation,
    • skin requiring intensive regeneration.

The best results are achieved when used as part of a comprehensive skincare program that includes professional cosmetology treatments and appropriately selected home care.

Synergistic Action of Centella Asiatica and Vitamin C

The combination of centella asiatica and vitamin C derivatives is one of the best-known synergies used in modern regenerative cosmetology.

Ascorbyl Glucoside is a stable vitamin C derivative that gradually releases the active form of ascorbic acid after penetrating the skin. It supports collagen synthesis, acts as an antioxidant, and helps even out skin tone.

The combination of centella asiatica and ascorbyl glucoside may support:

    • improvement of skin firmness and elasticity,
    • reduction of oxidative stress effects,
    • support of natural regenerative processes,
    • improvement of skin tone uniformity,
    • protection against premature aging.

Safety of Use

Centella asiatica is an ingredient that has been thoroughly studied in both laboratory and clinical research.

It is very well tolerated by most people; however, like other plant-derived ingredients, it may occasionally cause hypersensitivity reactions.

The risk of adverse effects is low, especially when products are used according to the recommendations of the manufacturer and skincare professional.


Why Does Centella Asiatica Play a Key Role in Beroe Sense Products and Therapies?

At Beroe Sense, we utilize the potential of centella asiatica (Centella asiatica) in its most advanced biotechnological form. Professional Beroe Sense ampoules have been developed using centella asiatica-derived exosomes, which support the skin’s natural regenerative processes and form the foundation of the brand’s proprietary cosmetology therapies.

Exosomes belong to the group of extracellular vesicles (EVs), which participate in intercellular communication and transport biologically active molecules supporting skin regeneration. Beroe Sense products contain exosomes derived from centella asiatica callus cultures grown under controlled in vitro conditions. The use of callus culture technology enables the production of highly pure raw material with consistent composition and quality, independent of environmental conditions. This is a modern biotechnological solution that complies with the highest standards of quality and sustainability.

This technology has been incorporated into all professional Beroe Sense ampoules:

    • Deep Lifting Solution – lifting, biostimulation, and skin regeneration,
    • Pigment Control Cocktail – care for skin with hyperpigmentation and uneven skin tone,
    • Hydra Power Shot – intensive hydration and restoration of the hydrolipid barrier,
    • Derma Calming Control – care for sensitive, reactive skin and skin showing signs of inflammaging.

Each ampoule combines exosome technology with carefully selected active ingredients, creating advanced formulations intended for professional cosmetology therapies. As a result, Beroe Sense procedures support biostimulation, regeneration, and improvement of skin quality while addressing diverse skincare needs.

Did You Know?

Extracellular vesicles (EVs) are currently considered one of the most promising directions in modern regenerative cosmetology. Their ability to support intercellular communication makes them the subject of intensive scientific research and innovative biotechnological applications.

By Marta Górzyńska and Małgorzata Kotwica.

Bibliography

1.  Lee BC, Lee SY, Park KM. Biological activity of Centella asiatica and its application in dermatology. Int J Mol Sci. 2023;24(8):7031. [1]

2.  James JT, Dubery IA. Centella asiatica (L.) Urban: A Review of the Therapeutic and Cosmetic Potential. J Ethnopharmacol. 2009;124(3):331–342. [1]

3.  Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, Brzezińska M. Centella asiatica (L.) Urban – właściwości biologiczne i zastosowanie w kosmetologii oraz medycynie. Postępy Fitoterapii. 2013;4:277–284.

4.  Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, i wsp. Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. J Extracell Vesicles. 2024;13(2):e12404. [1]

5.  Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, i wsp. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018;7(1):1535750. [1]

6.  Yáñez-Mó M, Siljander PRM, Andreu Z, Bedina Zavec A, Borràs FE, Buzas EI, i wsp. Biological properties of extracellular vesicles and their physiological functions. J Extracell Vesicles. 2015;4(1):27066.

7.  Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866.

8.  Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14–17.

9.  Kim HS, Kim YG, Kim M, Oh Y, Cho HE, Jee G, i wsp. Plant-derived extracellular vesicles as emerging therapeutic nanoplatforms. Adv Drug Deliv Rev. 2023;201:115066.

10.  Park SY, Kim KS, Lee YJ, Shin S, Kim JY, Cho KM, i wsp. Plant extracellular vesicles: Current applications and future perspectives in regenerative medicine and cosmetics. Pharmaceutics. 2024;16(2):241.

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24
Sep

We hosted a live webinar with cosmetologist Małgorzata Kotwica, co-creator of our formulas and protocols. She explained the four steps behind every Beroe Sense protocol, introduced Micel Pur, Lumina Veil and Post Ritual, and answered 21 questions from salon professionals. Topics included how often to microneedle, how to combine our cocktails with RF, IPL and HIFU, and what to offer clients with reactive skin.

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